Anti-UACA autoantibody in thyroid-associated ophthalmopathy
10.3760/cma.j.issn.1000-6699.2012.05.010
- VernacularTitle:血清UACA自身抗体在甲状腺相关眼病中的研究
- Author:
Jun LIU
;
Jian WANG
- Publication Type:Journal Article
- Keywords:
Thyroid-associated ophthalmopathy;
Uveal autoantigen with coiled coil domains and ankyrin repeats
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(5):402-403
- CountryChina
- Language:Chinese
-
Abstract:
Serum anti-uveal autoantigen with coiled coil domains and ankyrin repeats (UACA) antibody titer was measured using ELISA in 32 patients with thyroid-associated ophthalmopathy ( TAO ) and 20 patients with Graves' disease (GD) without ophthalmopathy.The level of anti-UACA antibody in TAO group was higher than that in GD group [ (225.91 ± 144.21 vs 187.42 ± 46.77 ) pg/ml,P＜0.05 ],and especially higher in patients with ocular myopathy [ (254.35 ± 168.29 ) pg/ml ].It seems that anti-UACA antibody is the sensitive clinical marker of ocular myopathy in TAO patients.
