Two Cases of Hypersexuality Probably Associated with Aripiprazole.
- Author:
Eunjin CHEON
1
;
Bon Hoon KOO
;
Sang Soo SEO
;
Jun Yeob LEE
Author Information
1. Department of Psychiatry, Yeungnam University College of Medicine, Yeungnam University Medical Center, Daegu, Republic of Korea. vijnana@chol.com
- Publication Type:Case Report
- Keywords:
Aripiprazole;
Hypersexuality;
Dopamine;
Partial agonist
- MeSH:
Antipsychotic Agents;
Dopamine;
Felodipine;
Female;
Humans;
Piperazines;
Quinolones;
Schizophrenia;
Aripiprazole
- From:Psychiatry Investigation
2013;10(2):200-202
- CountryRepublic of Korea
- Language:English
-
Abstract:
Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desire and greater sexual preoccupation after taking aripiprazole. We discuss the potential neuro-chemical mechanisms for this and argue that aripiprazole's unique pharmacological profile, partial agonism with high affinity at dopamine D2-receptor, may have contributed to the development of these symptoms.
