Comparison of the efficacy of metoprolol and nifedipine in the treatment of asymptomatic myocardial ischemia for the elderly
10.3760/cma.j.issn.1008-6706.2012.08.012
- VernacularTitle:美托洛尔与硝苯地平治疗老年人无症状性心肌缺血的疗效对比
- Author:
Yuerong LIU
;
Yongxia BO
;
Lixia SU
- Publication Type:Journal Article
- Keywords:
Metoprolol;
Nifedipine treatment;
Silent myocardial ischemia
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;(8):1143-1144
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the clinical value of application of metoprolol and nifedipine in the treatment of asymptomatic myocardial ischemia for the elderly.Methods56 cases of elderly patients with silent myocardial ischemia were chosen.They were randomly divideded into the metoprolol group of 28 cases and nifedipine group with 28 cases according to the number table.The incidence of complications during treatment in the metoprolol and nifedipine group were analyzed.The seizure frequency and onset time in the two groups of patients were compared before and after treatment.ResultsThe onset time in the two groups,before treatment had no statistically significant difference[the number of attacks:(19.6±3.2) times/week compared with(18.9±2.8) times/week;attack time:(5131±352)s vs (5130 ± 348 ) s,all ( P ＞ 0.05 ).After treatment,there were statistically significant differences for the number of attacks and attack time [the number of attacks:(4.6 ± 2.1 ) times/week compared with ( 7.4 ± 2.1 )times/week,onset tine:(900 ± 140) s vs ( 1440 ± 240 ) s ( all P ＜ 0.05 ).All patients can tolerate the treatment period,there was no cases of myocardial infarction occurs.ConclusionThe metoprolol and nifedipine for the elderly treatment of silent myocardial ischemia was more secure,and metoprolol was more effective than nifedipine.
