Clinical study of hyperbaric oxygen combining conventional therapy on traumatic brain injury with persistent vegetative state
10.3760/cma.j.issn.1008-6315.2012.06.029
- VernacularTitle:高压氧加常规治疗颅脑外伤后持续性植物状态的临床研究
- Author:
Zhirong ZHAO
;
Lifeng PAN
;
Aiping WU
;
Shizhu HAO
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Traumatic brain injury;
Persistent vegetative state
- From:
Clinical Medicine of China
2012;28(6):639-641
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy and mechanism of hyperbaric oxygen combining conventional therapy on persistent vegetative state ( PVS).Methods Sixty-two cases of PVS patients were treated with hyperbaric oxygen ( HBO ) combinting with conventional therapy.( 1 ) Hyperbaric oxygen therapy:hyperbaric oxygen chamber was adopted and the air pressure was 0,18 -0.20 MPa.The patients breathed pure oxygen for 30 min,2 times per day with a 10 min interval,and continued for 10 days as a course with an average of 4 to 6 courses.(2)Conventional therapy:All patients received drug treatment in hyperbaric oxygen therapy at the same time,including hemostasis,dehydration,anti-infection,nerve cell nutrition agents,wake promoting agents and supportive therapy.All patients were divided to three groups according to the course of disease:26 - 59 days in A group,60-119 days in B group,120 -268 days in C group,and the relationship between disease course and HBO treatment efficacy was analyzed.Results Afer HBO combining conventional therapy,27 cases (43.5％) were recovered,18 cases(29.0％ ) had obvious effect,8 cases( 12.9％ ) had effect,9 cases( 14.5％ )were inefficacy.The efficiency related to the course of disease.The total efficiency rate was 85.5％.The efficacy of HBO treatment had significant difference in A,B and C group ( 96.2％,62.5％ and 41.7％ in A,B and C group respectively,x2 =24.83,P ＜ 0.01 ).The shorter course indicated the better efficacy.Conclusion Hyperbaric oxygen combining conven.
