Acquired Gitelman syndrome associated with primary Sj(o)gren syndrome: two cases report and review of literature
10.3760/cma.j.issn.1007-7480.2012.05.011
- VernacularTitle:干燥综合征合并获得性Gitelman综合征二例并文献复习
- Author:
Xudong LIU
;
Haina LIU
;
Fang FANG
;
Bailing TIAN
;
Pingting YANG
;
Weiguo XIAO
- Publication Type:Journal Article
- Keywords:
Sj(o)gren syndrome;
Hypokalemia;
Gitelman's syndrome
- From:
Chinese Journal of Rheumatology
2012;16(5):333-335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To better understand the clinical features and the diagnosis of acquired Gitelman syndrome associated with primary Sj(o)gren syndrome (SS).Methods Two cases of acquired Gitelman syndrome associated with primary SS were investigated.Literature were reviewed.Results Two women with sicca complex presented to our clinic with intermittent muscle cramping and weakness involving both lower extremities for several months.Laboratory findings showed hypokalemic metabolic alkalosis, hypomagnesemia, and hypocalciuria,all these met the criteria for Gitelman syndrome.Diagnostic evaluation identified primary SS as the cause of the acquired Gitelman syndrome.Conclusion Acquired Gitelman syndrome associated with SS is rare.Kidney biopsy is necessary for the diagnosis of Gitelman syndrome.Further studies are needed.
