The role of middle hepatic vein on early remnant liver function and regeneration in the donor liver in adult-adult living donor liver transplantation
10.3760/cma.j.issn.1007-8118.2012.05.001
- VernacularTitle:成人右半肝活体肝移植切取肝中静脉对供者早期残肝功能和再生的影响
- Author:
Wentao JIANG
;
Qingjun GUO
;
Honghai WANG
;
Zhijun ZHU
;
Cheng PAN
;
Yonglin DENG
;
Hong ZHENG
;
Zhongyang SHEN
- Publication Type:Journal Article
- Keywords:
Living donor liver transplantation;
Liver function;
Regeneration
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(5):321-324
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the role of middle hepatic vein (MHV) on the early function and regeneration of the donor remnant liver in living donor liver transplantation (LDLT).Methods Between August 2007 and August 2008,66 LDLT were performed,36 without MHV (group A),and 30 with MHV (group B) in the donor liver.The donor operation time,intraoperative blood loss,postoperative hospital stay,serum bilirubin,international normalized ratio (INR),alanine aminotransferase (ALT) and albumin were analyzed.We measured the volume of remnant liver with CT scan at 2 weeks after operation,and compared the function and regeneration of the remnant liver between the two groups. Results At 2 weeks after operation,there was no significant difference (P=0.16) in the volume of remnant liver between group A (959.3±195.2 ml) and group B (883.7±155.5 ml).There was also no difference (P=0.62) in the regeneration rate of segment IV between group A (78.2 ％ ± 29.1 ％) and group B (82.7 ％ ± 40.4％).The serum bilirubin,INR and ALT in group B was significantly higher than group A immediately after liver transplantation,but there was no difference at 1 week after transplantation.ConclusionExtended right hepatectomy with MHV was safe,and did not significantly impact early liver function and regeneration in the donor.
