Predicting acute rejection in transplanted liver with virtul touch tissue quantification technique: a preliminary study
10.3760/cma.i.issn.1004-4477.2012.05.009
- VernacularTitle:声触诊组织量化技术检测移植肝急性排异的初步研究
- Author:
Hong HAN
;
Zhengbiao JI
;
Hong DING
;
Hui ZHANG
;
Wenping WANG
;
Ruixue WEI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Liver transplantation;
Graft rejection;
Virtual touch tissues quantification
- From:
Chinese Journal of Ultrasonography
2012;21(5):390-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the viability of virtual touch tissue quantification (VTQ)technique in the prediction of acute rejection in transplanted liver.Methods One hundred and eighteen patients enrolled in the study were categorized into four groups:normal control (n =31),cirrhosis ( n =29),transplanted liver with acute rejection (n =28),transplant liver without any complications (n =30).All the patients were confirmed by pathology or clinical results.The VTQ of right robe of liver was obtained by a ultrasound system with VTQ technique and the data was compared among the four groups.Results The VTQ was (1.10 ± 0.29)m/s,(1.33 ± 0.33) m/s,(1.81 ± 0.47) m/s and (2.12 ± 0.59) m/s in normal control,transplanted liver without any complications,transplanted liver with acute rejection and cirrhosis group,respectively.It was significantly different in all four groups (P＜0.01).Patients with acute rejection were associated with the increase of the VTQ values (P＜0.01).Using a cutoff of VTQ＞1.36 m/s measured in the transplanted liver for prediction of acute rejection,the sensitivity and specificity were 82.1％ and 68.2％.Conclusions VTQ technique may have some clinical value in evaluation the acute rejection in transplanted liver.
