Fatal Intracranial Hemorrhage in a Patient with Disseminated Intravascular Coagulation associated with Sepsis.
10.4266/kjccm.2016.31.2.134
- Author:
Hyun Jin BAEK
;
Doo Hyuk LEE
;
Kyu Hyung HAN
;
Young Min KIM
;
Hyunbeom KIM
;
Byeongwook CHO
;
Inkuk LEE
;
Kanghyun CHOI
;
Hojin YONG
;
Goohyeon HONG
- Publication Type:Case Report
- Keywords:
disseminated intravascular coagulation;
intracranial hemorrhage;
sepsis
- MeSH:
Blood Platelets;
Critical Illness;
Dacarbazine;
Disseminated Intravascular Coagulation*;
Ecchymosis;
Gastrointestinal Tract;
Hemorrhage;
Humans;
Intracranial Hemorrhages*;
Male;
Middle Aged;
Mortality;
Plasma;
Sepsis*
- From:Korean Journal of Critical Care Medicine
2016;31(2):134-139
- CountryRepublic of Korea
- Language:English
-
Abstract:
In critically ill patients, disseminated intravascular coagulation (DIC) is a common and fatal hematological disorder. DIC is a physiological response to a variety of underlying stimuli that provoke generalized activation of the hemostatic mechanism and is common in septic patients and those with hematological or non-hematological malignant neoplasms. Bleeding is a common clinical feature, and diffuse or multiple-site mucocutaneous bleeding, such as petechia, ecchymosis and hemorrhage from gastrointestinal tract, is often seen. A 58-year-old male was recently diagnosed with intracranial hemorrhage (ICH) caused by DIC associated with sepsis. Mortality of ICH caused by DIC is very high because the underlying condition cannot be quickly treated. Awareness of the possibility of DIC developing in a critically ill patient and the need for immediate initiation of plasma or platelet replacement therapy are important. To the best of our knowledge, this is the first reported case of intracranial hemorrhage in a Korean patient with DIC associated with sepsis.
