Acute Respiratory Failure due to Alveolar Hemorrhage after Exposure to Organic Dust.
10.4266/kjccm.2016.31.2.173
- Author:
Sun Mi CHOI
;
Jiwon KOH
;
Sang Min LEE
;
Jinwoo LEE
- Publication Type:Case Report
- Keywords:
hemoptysis;
hemorrhage;
organic;
respiratory insufficiency
- MeSH:
Adrenal Cortex Hormones;
Adult;
Anti-Bacterial Agents;
Biopsy;
Bronchoalveolar Lavage;
Diagnosis, Differential;
Dust*;
Fibroblasts;
Hemoptysis;
Hemorrhage*;
Humans;
Intensive Care Units;
Lung;
Macrophages;
Respiration, Artificial;
Respiratory Insufficiency*
- From:Korean Journal of Critical Care Medicine
2016;31(2):173-177
- CountryRepublic of Korea
- Language:English
-
Abstract:
Diffuse alveolar hemorrhage (DAH) is associated with severe outcomes. We report a case of acute respiratory failure that required mechanical ventilation and was clinically and pathologically diagnosed as DAH related to exposure to organic dust. A 39-year-old man, who had visited a warehouse to grade beans for purchase, was referred to our hospital for impending respiratory failure. His initial radiographic examinations revealed diffuse bilateral ground-glass opacities in his lungs and bronchoalveolar lavage resulted in progressively bloodier returns, which is characteristic of DAH. He underwent bedside open lung biopsy of his right lower lobe in the intensive care unit. Biopsy results revealed DAH and organization with accumulation of hemosiderin-laden macrophages and a few fibroblastic foci. The patient was treated with empirical antibiotics and high-dose corticosteroids and successfully weaned from mechanical ventilation. DAH might be considered in the differential diagnosis of patients with acute respiratory failure after exposure to organic particles.
