Clinical analysis of thyroid hormone tablets in the treatment of patients with primary nephritic syndrome and hypothyroidism
10.3760/cma.j.issn.1008-6706.2012.06.011
- VernacularTitle:左旋甲状腺素治疗原发性肾病综合征并甲状腺功能减退症的临床观察
- Author:
Junhui LI
- Publication Type:Journal Article
- Keywords:
Nephrosis;
Hypothroidism;
Thyroid hormones
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(6):822-823
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the effects of thyroid hormone tablets on the outcome of patients with primary nephritic syndrome.MethodsRadioimmunoassay(RIA) was used to determine the level of serum FT3,FT4 and TSH before and after the routine treatment in 36 healthy patients and 72 patients with primary nephritic syndrome and hypothyroidism.The curative effect of thyroid hormone tablets was observed.ResultsThe levels of FT3 and FT4 [ (1.67 ± 0.39)pmol/L,(8.3 ± 2.2 )pmol/L] in patients group were significantly lower than that in control group (t =12.635,16.304,P =0.041,0.032 ).But the level of TSH was not different before and after treatment( t =2.245,P ＞0.05).The levels of FT3 and FT4 after treatment were higher than before treateat (P ＜0.01 ).At the corresponding period,the levels of FT3 and FT4 in the observation group with thyroid hormone tablets were significantly higher than that in the group with routine treatment.At the same time,the treatment time for complete remission was also shorter,and after 12 months the catabatic rate (72.2％) was higher than routine treatment( x2 =21.04,P ＜0.05 ).ConclusionTreatment with,thyroid hormone tablets could shorten the course of the disease and increase the catabatic rate.
