The efficacy evaluation of carvedilol in the treatment of 60 chronic heart failure patients with arrhythmias
10.3760/cma.j.issn.1008-6706.2012.06.020
- VernacularTitle:卡维地洛治疗慢性心力衰竭并心律失常60例疗效分析
- Author:
Weining CHEN
- Publication Type:Journal Article
- Keywords:
Heart failure,congestive;
Arrhythmia;
Carvedilol
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(6):839-841
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the clinical effect of carvedilol in the treatment of chronic heart failure patients with arrhythmia.Methods120 cases of hospitalized cases of cardiology were randomly divided into treatment and control groups by checking the random number table.The control group was given benazepril hydrochloride combined digoxin cardiac medicine and furosemide or hydrochlorothiazide,spironolactone and other diuretics in the treatment.The treatment group was given carvedilol based on the treatment of the control group.Followed up for 12 weeks,the clinical manifestations,blood pressure and heart rate,left ventricular ejection fraction(EF) and arrhythmias before and after treatment were obsered,and to determine the efficacy.ResultsThe treatment group decreased heart rate,corrected ventricular premature contraction,ventricular contraction and ventricular tachycardia in comparison with the control group with significant differences(t =6.018、5.319、7.623、6.194、7.562,all P ＜0.001 ),and there was a significantly statistical significance( P ＜ 0.01 ) that the treatment group can increase the ejection fraction compared with the control group.The markedly and total efficiency was more effective in the treatment group than the control group,which was statistically significant(x2 =34.301,P ＜0.05).ConclusionThere was a positive effect of carvedilol in improving heart function,reduceing arrhythmias and mortality,and reducing hospitalization rate and other aspects.
