Study on the relationship between the change of serum lipid and pathological change of coronary artery in Kawasaki disease children
10.3760/cma.j.issn.1008-6706.2012.06.035
- VernacularTitle:川崎病患儿血脂水平与冠状动脉损害的关系研究
- Author:
Peilin XU
- Publication Type:Journal Article
- Keywords:
Mucocutaneus lymph node syndrome;
Coronary disease;
Cholesterol;
Lipoproteins
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(6):868-869
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the relationship between the change of serum lipid and pathological change of coronary artery in Kawasaki disease(KD) children.Methods62 children with pathological change of coronary artery in KD were divided into pathological of coronary artery group and normal coronary artery group.62 normal children were selected as control group in the same time.And then the serum lipid status of three groups were compared.ResultsThe TC (5.32 ± 1.74 ) mmol/L,( 5.24 ± 1.67 ) mmol/L,TG ( 1.67 ± 0.79 ) mmol/L,( 1.74 ± 0.65 ) mmol/L,LDL-C(2.87 ± 1.14 ) mmol/L,( 2.72 ± 1.08 ) mmol/L of KD of the two groups were lower than of the control group(3.08 ± 1.28) mmol/L,( 1.12 ±0.56) mmol/L,(2.37 ± 1.06) mmol/L(t =1.70,1.66,1.71,all P ＜0.05 ),and HDL-C( 1.03 ± 0.31 ) mmol/L,( 1.08 ± 0.57 ) mmol/L higher than that of the control group ( 1.65 ± 0.92 )mmol/L( t =1.54,P ＜ 0.05 ) ; There were no differences between two coronary artery groups.After treated,TC,TG,LDL-C of normal coronary artery group were decreased ( t =1.76,1.88,1.72,all P ＜ 0.05 ),and HDL-C was increased ( t =1.90,P ＜ 0.05 ).ConclusionThe child ren with KD had dyslipidemia,and the dyslipidemia was recovered slowly.So,it should be an index of early diagnose for KD with coronary artery lesion.
