Analysis of the cause of death in 31 severe organophosphorus poisoning

VernacularTitle:重症有机磷中毒31例致死原因分析
Author: Zhizhong SUN
Publication Type:Journal Article
Keywords: Organophosphate poisoning; Cholinergic crisis; Respiratory failure; Cause of death
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(5):667-668
CountryChina
Language:Chinese
Abstract: Objective To explore cause of death and the lessons learned in critically ill patients with organophosphate poisoning.Methods The clinical manifestations,treatment,cause of death in 31 patients with severe organophosphate poisoning deaths were retrospectively analyzed.Results 31 deaths of patients,12 patients died of cholinergic crisis(38.70％),16 patients died of respiratory failure(51.61％),2 patients died of atropine intoxication (6.45％),1 patient died of the solution be excessive phosphorus(3.23％).6.01％ incidence of intermediate syndrome,mortality was 16.94％.Conclusion Poison not completely clear,atropine and cholinesterase agents applied inappropriately,patients with mechanical ventilation for respiratory failure improper treatment,the merger is an important organ of the original basis of disease leading cause of death,accurately determine the condition is the key to reducing mortality.