Allogeneic stem cell transplantation in multiple myeloma
10.3760/cma.j.issn.1673-422X.2012.04.019
- VernacularTitle:异基因干细胞移植治疗多发性骨髓瘤
- Author:
Shiqiu ZHOU
;
Shifeng LOU
;
Yun LUO
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Stem cell transplantation;
Therapeutics
- From:
Journal of International Oncology
2012;39(4):301-304
- CountryChina
- Language:Chinese
-
Abstract:
Allogeneic stem cell transplantation is the only treatment which may cure multiple myeloma (MM).The high transplantation related mortality (TRM) limits the wide clinical application of myeloablative allogeneic stem cell transplantation.Non-myeloablative allogeneic stem cell transplantation can reduce the TRM,but the risk of relapse and progress of the disease may get increased. Autononmyeloablative allogeneic stem cell tandem transplantation can reduce both the TRM and the relapse and progress of the disease. At present,there exist many new methods which may improve the effect of allogeneic stem cell transplantation for MM in clinical.