Tumor microenvironment and neoadjuvant chemotherapy in breast cancer
10.3760/cma.j.issn.1673-422X.2012.04.010
- VernacularTitle:微环境与乳腺癌新辅助化疗
- Author:
Guohua RONG
;
Hua KANG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Chemotherapy,adjuvant;
Chemokine CXCL12;
Microenvironment
- From:
Journal of International Oncology
2012;39(4):272-274
- CountryChina
- Language:Chinese
-
Abstract:
Recently many studies have focused on the roles that tumor microenvironment plays in the occurrence and development of tumors,and the therapeutic effects of adjuvant chemotherapy and neoadjuvant chemotherapy.Recent researches show that tumor microenvironment has an obvious impact on the therapeutic effects of neoadjuvant chemotherapy,which mainly includes cancer-associated fibroblasts (CAF),stromal cell derived factor-1 (SDF-1) and collagens.
