Epigenetic regulation and gastric cancer
10.3760/cma.j.issn.1673-422X.2012.04.016
- VernacularTitle:表观遗传调控与胃癌
- Author:
Ji CHEN
;
Dingyi LIU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Epigenesis, genetic;
DNA methylation;
Histone code;
MicroRNAs
- From:
Journal of International Oncology
2012;39(4):292-295
- CountryChina
- Language:Chinese
-
Abstract:
The initiation and development of gastric cancer is due to the effects from both external and internal factors.Recent researches show that external environment factors regulate and control the key genes expression during the process of cell's growth and development through epigenetic modification such as DNA methylation or demethylation,histone modification and small RNA,thus playing an important role in gastric cancer's occurrence and development.
