Molecular targeted therapy of diffuse large B cell lymphoma
10.3760/cma.j.issn.1673-422X.2012.04.022
- VernacularTitle:弥漫大B细胞淋巴瘤的分子靶向治疗
- Author:
Guorong YANG
;
Meizuo ZHONG
- Publication Type:Journal Article
- Keywords:
Lymphoma,large B-cell,diffuse;
Molecular targeted therapy
- From:
Journal of International Oncology
2012;39(4):311-315
- CountryChina
- Language:Chinese
-
Abstract:
The diffuse large B cell lymphoma (DLBCL) is the most common adult non-hodgkin lymphoma.At present,rituximab in combination with CHOP program has significantly improved the prognosis of DLBCL,and about 50％ of the DLBCL can be cured.However,due to the heterogeneity of the tumor,the refractory and relapsed DLBCL is still lack of effective treatment methods.With the application of gene expression profile (GEP) and the thorough research of the activation of lymphoma cells signal way,a lot of potential therapeutic targets have been found.
