The clinical significance of IMT and PWV in type 2 diabetic patients
10.3760/cma.j.issn.1008-6706.2012.05.011
- VernacularTitle:糖尿病患者颈动脉内中膜厚度、脉搏波传导速度测定的临床意义
- Author:
Yanfeng GUI
;
Libo CHEN
;
Changning ZHANG
;
Liping LI
;
Jianfen GU
;
Qiang YE
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Intima-media thickness;
Pulse wave velocity
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(5):665-666
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between intima-media thickness(IMT)and pulse wave velocity(PWV)in patients with type 2 diabetes mellitus.Methods 100 cases with type 2 diabetes were randomly divided into:hydrochlorothiazide group of 35 cases,valsartan group of 35 cases,valsartan and hydrochlorothiazide combined treatment group(combined group)30 cases.All the patients were treated for 16 weeks,systolic blood pressure (SBP),diastolic blood pressure(DBP),24h urinary albumin,blood urea nitrogen(BUN),carotid IMT,PWV,fasting plasma glucose(FPG)were measured before and after treatment in each group.Results The SBP,DBP,24h urinary albumin before treatment compared with after treatment was significant differences in three groups(t =2.7875,2.755,2.733,2.645,all P ＜ 0.05); IMT associated with SBP(r =0.669,P =0.013),pulse pressure(r =0.581,P =0.015),FPG(r =0.337,P =0.018);PWV associated with SBP(r =0.759,P =0.001),pulse pressure(r =0.707,P=0.002),FPG(r =0.679,P =0.016).Conclusion The non-invasive indicators of PWV can be used as aortic compliance.The PWV measurement of its vascular complications has important clinical value.
