The effect of ω-3 fish oil on nutrition improvement and inflammatory reaction of patients with gastrointestinal tumor after operation
10.3760/cma.j.issn.1008-6706.2012.04.020
- VernacularTitle:鱼油对胃肠肿瘤患者术后营养状况改善及炎性反应的影响
- Author:
Yuliang ZHANG
;
Caihua ZHANG
;
Zhenguo ZHAO
;
Fengtao LIU
;
Wu JI
- Publication Type:Journal Article
- Keywords:
Fish oil lipid emulsion;
Parenteral nutrition;
Gastrointestinal tumors;
Inflammatory factor;
Postoperative
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(4):519-521
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of ω-3 fish oil on nutrition improvement and inflammatory reaction of patients with gastrointestinal tumor after operation.Methods 60 cases with gastrointestinal tumor were divided into control group(30 cases) and study group (30 cases),both groups were provided with parenteral nutrition treatment[ 104.6 kJ · kg-1 · d-1 ].Fish-oil fatty emulsion was given to the study group.The postoperative for the first day received half of the total energy and the total energy The remaining four days.Blood samples were gained on the morning of day 1,on the morning of day 3 and day 6 after operation respectively to measure albumin ( ALB),prealbumin (PA),total protein(TP),transferrin(TRF),the neutrophilic granulocyte count,lymphocyte count (TLC),serum C-reactive protein(CRP).Results Both groups of patients was comparable(all P < 0.05 ).Both groups of patients was treated after five days of postoperative and ALB,TP,TRF were not significantly different.PA in both groups on day 6 was significantly increased,and the study group was higher than control group.there were statistical differences between them ( all P < 0.05 ).The neutrophilic granulocyte count and CRP of both groups were significant reduced,and the study group was lower than control group.There were statistical differences between them( all P <0.05 ).Conclusion ω-3 fish oil on nutrition could improve nutritional quality and modulate inflammatory reaction of patients with gastrointestinal tumor after operation.