Influence of neo-adjuvant chemotherapy on progrsssive gastric cancer operation withi multi-disciplinary team
10.3760/cma.j.issn.1008-6706.2012.03.026
- VernacularTitle:多学科协作下新辅助化疗对进展期胃癌手术效果的影响
- Author:
Fengqiang ZHOU
;
Yanmei QI
;
Huiguang GUO
;
Hong XU
;
Shilu JIN
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Surgical procedures,Operative;
Antineoplaatic combined chemotherapy protocols;
Multi-disciplinary team (MDT)
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(3):373-375
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the influence of the progress and result in gastic cancer operation through application of neo-adjuvant chemotherapy in multi-disciplinary team (MDT).Methods Clinical data of the patients treated in MDT model 45 cases and non-MDT model(78 cases) were respectively analyzed,and the index about pathologic change,histologic transform and operative result between the two groups were compared.Results In the index of pathologic change,the incidence of abdominal adherence and ascites and pyloric obstruction in MDT model group were obviously less than non-MDT model group( P ＜0.05 ).In the index of histologic transform,texture of mesentery in MDT model group was more fragile than non-MDT model group( P ＜0.05).In the index of operative results,the operative duration and intra-operative bleeding in MDT model group were less than non-MDT model group (P ＜0.05).Conclusion Neo-adjuvant chemotherapy has certain influence in gastric caneer operation,but the successful operations were performed by standard and correct procedures.Therefore,optimizing combined therapy in MDT model and constructing preoperative evaluation system with neo-adjuvant chemotherapy.
