Serous microcystic adenoma of pancreas: a clinicopathological study

VernacularTitle:胰腺浆液性微囊性腺瘤临床病理分析
Author: Bo CHEN ; Xinghao NI ; Youhua JIANG ; Guoping CHENG ; Pingding KUANG ; Junying CHEN
Publication Type:Journal Article
Keywords: Pancreas; Serous microcystic adenoma; Clinicopathological analysis
From: Chinese Journal of Hepatobiliary Surgery 2012;18(3):176-179
CountryChina
Language:Chinese
Abstract: Objective To study the clinicopathological features in the diagnosis of serous microcystic adenoma of pancreas.Method A clinicopathological and immunohistochemical study was conducted on 7 patients with serous microcystic adenoma of pancreas.Results All the patients were female,with a mean age of 51 years.Clinical symptoms were present in 2(28.6％)patients.On microscopy,the tumor composed of variable-sized cysts.The cyst wall was covered by simple cuboidal epithelium.The cytoplasm was clear and glycogen-rich.The nucleus of the epithelial cells was small and round.In the center,there was no nucleolus and no nuclear division.There were bulky fibrous tissues between the cystic cavities.Immunohistochemical study showed AE1/AE3,CK7,CK8,CK19,CK/LMW,EMA were positive,and CEA,CD31,CD34,D2-40,Syn,CgA,Calretinin,Vim were negative.Conclusions Serous microcystic adenoma of pancreas is a rare tumor,which was common in old women.Serous microcystic adenoma of pancreas is a benign tumor with good prognosis.The diagnosis is made on histopathological and immunohistochemical study.