Clopidogrel resistance and the prevention and treatment of stroke
10.3760/cma.j.issn.1673-4165.2012.03.012
- VernacularTitle:氯吡格雷抵抗与卒中防治
- Author:
Lian HUANG
;
Shijun ZHANG
;
Anding XU
;
Xuewen SONG
- Publication Type:Journal Article
- Keywords:
Clopidogrel;
Drug Resistance;
Platelet Aggregation Inhibitors;
Stroke;
Brain Ischemia
- From:
International Journal of Cerebrovascular Diseases
2012;20(3):219-222
- CountryChina
- Language:Chinese
-
Abstract:
Clopidogrel is an essential drug for the treatment of ischemic stroke.It has been recommended by the multinational stroke treatment guidelines and has been widely used in clinical practice.Many patients with ischemic stroke may still have stroke recurrence after the standard treatment of clopidogrel; therefore,we must pay attention to the phenomenon of clopidogrel resistance.This article reviews the biochemical mechanisms,gene polymorphism,laboratory testing,and response measures of clopidogrel resistance.
