Observation on the changes of serum bilirubin and high-sensitivity C-reactive protein in acute myocardial infarction patients after percutaneous coronary intervention
10.3760/cma.j.issn.1008-6706.2012.03.010
- VernacularTitle:冠状动脉介入治疗急性心肌梗死患者血清胆红素和超敏C-反应蛋白变化
- Author:
Huixia MA
;
Hongmei MO
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Angioplnsty,transluminal,percutaneous coronary;
C-reactive protein;
Bilirubin
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(3):339-340
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of serum bilirubin(BIL) and high-sensitivity C-reactive protein(hs-CRP) after percutaneous coronary intervention(PCI) in acute myocardial infarction(AMI) patients.Methods The TBiI,IBil,DBil and hs-CRP levels in serum were detected in 60 AMI patients within 6 hours after attack with immunoturbidimetry before PCI,at the point of operation,6h,12h,24h,72h and 7d afer PCI.30 healthy persons were chosen as normal control.The two groups were compared.Results The hs-CRP level was increased gradually with time in AMI patients after PCI.The peak value was at 72h after PCI and it was significantly higher than those in the normal group( P ＜ 0.05 ).The TBil,IBil,DBil levels at pre-PCI point were significantly lower than the normal group (P ＜ 0.05).These index were gradually recovered to the normal group and no significancet differences between them (P ＞ 0.05 ).The coefficient correlation of hs-CRP and TBil,IBil,DBil were 0.44 ( P ＞ 0.05 ).Conclusion The TBil,IBil,DBil and hs-CRP levels in short time after attack of AMI with PCI presented a dynamic changing and recovered to the normal level.No associativity was observed between them,but as the follow-up index,it was significant for the disease turnover.
