MicroRNA biology technology and the progress research of miR-125 in disease
10.3760/cma.j.issn.1673-4203.2012.03.014
- VernacularTitle:MicroRNA生物技术与miR-125在疾病中的研究进展
- Author:
Jie MI
;
Hong GAO
- Publication Type:Journal Article
- Keywords:
MicroRNA;
Biology technology;
MiR-125
- From:
International Journal of Surgery
2012;39(3):188-191
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA,which is found in recent years,is a class of small noncoding RNAs of about 18-24 nucleotides in length,that can regulate gene expression.It induces mRNA degradation or inhibit translation of tagert genes mainly by complete or incomplete base pairing to the 3' untranslated region of tagert messenger RNAs.The application of microRNA biology technology provides new methods to the research of multiple diseases,and can further elucidate its occurrence,development mechanism.In this paper,microRNA biology-related researches are introduced and miR-125 in a variety of diseases is reviewed.
