Progression of genetic study in idiopathic hypogonadotropic hypogonadism
10.3760/cma.j.issn.1000-6699.2012.03.022
- VernacularTitle:特发性低促性腺激素性性腺功能减退症的遗传学研究进展
- Author:
Ruya LIU
;
Xiaoying LI
- Publication Type:Journal Article
- Keywords:
Idiopathic hypogonadotropic hypogonadism;
Genetics
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(3):244-248
- CountryChina
- Language:Chinese
-
Abstract:
Idiopathic hypogonadotropic hypogonadism(IHH) is a complex oligogenic disease.About 60% of patients are associated with anosmia or hyposmia,also known as Kallmann syndrome. Based on genetic and molecular biological research,about more than ten IHH responsible genes have been discovered.