Preliminary application of double contrast-enhanced ultrasonography to assess the peripancreatic vascular invasion of pancreatic carcinoma
10.3760/cma.j.issn.1004-4477.2012.03.010
- VernacularTitle:超声双重造影评价胰腺癌侵犯胰周血管的初步应用
- Author:
Shiyan LI
;
Pintong HUANG
;
Haishan XU
;
Lilong XU
;
Ke XU
;
Jianghong Lü
;
Bowen ZHAO
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Pancreatic neoplasms;
Vascular invasion
- From:
Chinese Journal of Ultrasonography
2012;21(3):209-212
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of double contrast-enhanced ultrasonography (DCEUS) in assessing the peripancreatic vascular invasion of pancreatic carcinoma.Methods Twenty-eight patients with pancreatic cancer confirmed by postoperative pathology were examined by DCEUS preoperatively.The relationship between neoplasms and peripancreatic vessels was analyzed for assessing whether vascular invasion of pancreatic cancer had occurred.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of DCEUS in evaluating vascular involvement were calculated by using the surgical results as a gold standard.Kappa test was used for assessing the intra- and interobserver reliability of DCEUS.Results In total 28 patients,21 cases were diagnosed as vascular invasion,whereas,7 cases were noninvasive by surgical results.By DCEUS,18 cases were assessed as positive involvement of vessels,whereas,10 cases were negative.The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of DCEUS in evaluating vascular involvement were 85.71 ％,100％,100 ％,70.00 ％ and 89.29 ％ respectively,and with higher reliability (Kappainter =0.75,Kappa =0.80).Conclusions DCEUS could be considered as a novel method to assess vascular invasion of pancreatic carcinoma accurately and reliably.
