Inflammatory pseudotumor-like follicular dendritic cell tumor of liver and spleen: a clinicopathological study
10.3760/cma.j.issn.1007-8118.2012.03.003
- VernacularTitle:肝脏和脾脏炎性假瘤样滤泡树突细胞肿瘤的临床病理分析
- Author:
Baoling TIAN
;
Aifeng GAO
;
Can XU
;
Hong SHU
;
Changjun JIA
;
Xianghong YANG
- Publication Type:Journal Article
- Keywords:
Inflammatory pseudotumor-like follicular dendritic cell tumor;
Liver tumor;
Spleen tumor
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(3):169-172
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinicopathological features and biological behavior of inflammatory pseudotumor-like follicular dendritic cell tumor.Methods We studied the clinical data,HE sections,immunohistochemical staining,Epstein-Barr virus encoded nuclear RNA(EBER)in situ hybridization and outcome of one patient with inflammatory pseudotumor-like follicular dendritic cell tumor of liver,and thirteen patients with inflammatory pseudotumor of liver and spleen treated at the Shengjing Hospital of China Medical University from 2001 to 2010.Results Among the thirteen inflammatory pseudotumors,we diagnosed 1 patient with inflammatory pseudotumor-like follicular dendritic cell tumor of spleen and 1 patient with inflammatory pseudotumor-like follicular dendritic cell tumor of liver using immuno-histochemical staining and EBER in situ by hybridization.The liver case had pathological morphology consistent with those described in the literatures,but the splenic case had specific histologic features.They were both female,and were alive 2.5 and 6 years after operation.Conclusions Inflammatory pseudotumor-like follicular dendritic cell tumor should be distinguished from inflammatory pseudotumor.It is a rare tumor seen mainly in liver and spleen.The diagnosis depends on histopathological and immunohistochemical findings.Inflammatory pseudotumor-like follicular dendritic cell tumor is a low-grade malignant tumor.Surgical excision is the treatment of choice.The two cases provided evidence for its indolent behavior.
