A Case of Systemic Lupus Erythematosus Involving the Kidneys in a Patient with IgA Nephropathy.
10.4078/jkra.2010.17.3.316
- Author:
Ji Eun SONG
1
;
Mi Young JANG
;
Wang Guk OH
;
Jeong Gwan KIM
;
Sung Hyun PARK
;
Ki Hoi KIM
;
Min Ho HWANG
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea. fishermen68@hotmail.com
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Lupus nephritis;
IgA nephropathy;
Subacute necrotizing lymphadenitis
- MeSH:
Biopsy;
Female;
Glomerulonephritis, IGA;
Humans;
Immunoglobulin A;
Kidney;
Lupus Erythematosus, Systemic;
Lupus Nephritis;
Lymphadenitis;
Nephritis;
Young Adult
- From:The Journal of the Korean Rheumatism Association
2010;17(3):316-320
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Renal involvement in systemic lupus erythematosus (SLE) is a typical manifestation of the disease. The occurrence of non-lupus nephritis, especially IgA nephropathy (IgAN), in patients with SLE has rarely been reported. We describe the case of a 21-year-old woman who was diagnosed with IgAN and subacute necrotizing lymphadenitis, and her renal lesion biopsy was typical of lupus nephritis (ISN/RPS Class III). Although IgAN and lupus nephritis share some common physiopathological characteristics, their laboratory, histopathologic findings, and the extra-renal clinical manifestations are different and support a different pathogenesis. Our case highlights the importance of a renal biopsy in patients with lupus and urinary alterations despite underlying IgAN. A correct diagnosis would permit the most appropriate immunosuppressive treatments to be considered.
