Ewing's sarcoma of the kidney: a case report and review of the literature
10.3760/ema.j.issn.1000-6702.2012.03.003
- VernacularTitle:肾脏未分化网状细胞肉瘤一例报告并文献复习
- Author:
Hongwei ZHAO
;
Junhang LUO
;
Yingrong LAI
;
Jian LU
;
Wei CHEN
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Sarcoma,Ewing's;
Pathology,clinical
- From:
Chinese Journal of Urology
2012;33(3):176-179
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo review the clinical features,management and prognosis of renal Ewing's sarcoma (ES) of a single case report.MethodsA single case of renal ES was reported.A 33-year-old male presented with a mass in the left kidney found during a three day medical examination.B-ultrasound examination showed a lesion with rich blood flow signals and well defined margins in the inferior portion of the left kidney.The CT scan revealed a solid mass of 5.1 cm × 4.7 cm in the inferior portion of the kidney with un-even enhancement by contrast.A possible diagnosis of renal carcinoma was given prior to surgery.No metastasis was proven.A literature review of ES was then conducted.ResultsA left retroperitoneoscopic radical nephrectomy was successfully performed.Gross pathologic examination showed a solid tumor with necrosis,localized at the inferior pole of the left kidney.The histopathological examination revealed the tumor consisted of small round tumor cells,which were positive for CD99,vimentin and PAS,but negative for WT-1.A diagnosis of ES of the kidney was then determined.The patient received alternating short cycle ( CTX + VCR + THP) and long cycle ( IFO + VP-16) adjuvant chemotherapy for 6 cycles after the operation.There has been no evidence of recurrence at the 14-month follow up.ConclusionsES of the kidney is a rare disease with no specific clinical feature in most cases.Diagnosis of renal ES must be confirmed with histological features.Surgery combined with radiotherapy and chemotherapy is the main method of therapy for renal ES.The prognosis of renal ES is poor.
