In vitro experimental study on removing low density lipoprotein with HB-H-8 resin adsorption
10.3760/cma.j.issn.1673-4181.2012.02.014
- VernacularTitle:HB-H-8树脂吸附低密度脂蛋白的体外实验研究
- Author:
Yichen LI
;
Liqun LUO
;
Tao LI
- Publication Type:Journal Article
- Keywords:
Low density lipoprotein;
High density lipoprotein;
Hemoperfusion;
Adsorption
- From:
International Journal of Biomedical Engineering
2012;35(2):121-124
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveCurrently,adsorption materials applied to remove low density lipoprotein (LDL) still remain defects.HB-H-8 resin has not been put in use in removing LDL.This study focused on primary evaluation of adsorption capability of HB-H-8 resin.MethodsHB-H-8 resin was used in the adsorption of LDL of patient that was higher than the normal range of blood sample in dynamic test and static test in vitro.ResultsThe time of adsorption saturation was two hours,and the optimum temperature was 37℃.The results of adsorption in vitro showed that the average adsorption rates of LDL and high density lipoprotein (HDL) were 63.2％ and 1.9％,respectively.ConclusionHB-H-8 resin has LDL higher adsorption capability,thus made it to be a potential blood purification material for the removal of LDL.
