The ERP brain topographic map study on mental rotation of depressions
10.3760/cms.j.issn.1674-6554.2012.02.013
- VernacularTitle:抑郁症患者心理旋转的事件相关电位脑地形图研究
- Author:
Jiu CHEN
;
Laiqi YANG
;
Guangxiong LIU
;
Xingqu WU
;
Yan ZHANG
;
Wentao MA
;
Zihe DENG
- Publication Type:Journal Article
- Keywords:
Depression;
Mental rotation;
Event-related potentials;
Brain topographic map
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2012;21(2):135-138
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the change of the event related potential brain topographic map on depression' mental rotation,and to perfect the brain function relation map for depression in space ability.Methods 32 depression and 29 normal healthy people were tested to make mental rotation tasks in the brain ERP system.The distribution of the changing brain topographic map were observed.Results ( 1 ) Compared with the control group ( error rate ( 29±9 ) ％,response time ( 604.74 ± 54.39 ) ms,the error rate was significantly higher and response time was significantly longer in depression (error rate( 33 ± 15 )％,response time(755.22 ± 70.18 )ms,P＜0.05).(2) Compared with the control group (N100:PZ( -3.78 ± 1.05)μV,CZ( -5.67 ±2.21)μV,P3( -2.34 ±0.59) μV,P4( -2.92 ±0.80) μV ;P500:PZ(7.35 ±2.61 ) μV,CZ(7.65 ± 2.42) μV,P3 (6.53 ±2.11 ) μV,P4 ( 7.29 ± 2.57 ) μV ),the total volatility was significantly lower in depression ( N 100:PZ ( - 0.31 ±0.09)μV,CZ( -2.27 ±0.57)μV,P3( -0.30 ±0.07) μV,P4( -0.33 ±0.08) μV;P500:PZ(6.04 ±2.16)μV,CZ ( 5.92 ± 2.01 ) μV,P3 ( 6.02 ± 2.11 ) μV,P4 (6.01 ± 2.34 ) μV,P ＜ 0.05 ) and the excitability difference of the left and right parietal-occipital lobe was disappeared (P＞0.05) ; Compared with the control group,in N100 the normal and mirror excitability was significantly lower,and in P500 the normal excitability was significantly lower,but mirror was significantly higher in depression (P ＜ 0.05 ).Compared with the left and right brain,the normal excitability in the right parietal-occipital lobe was significant higher (P ＜ 0.05 ),but the mirror excitement difference was disappeared in depression (P＞ 0.05 ),and the normal and mirror excitement in the right parietal-occipital lobe was both significantly higher in normal healthy people (P ＜ 0.05 ).ConclusionDepressed patients; mental rotation ability is impaired.And the negative potential for looking forward to reaction is lower and exist the right advantage hemisphere brain in normal,but mirror advantage hemisphere disappears in depressed patients.This study suggests the brain topographic map of mental rotation ability damaged can be used as the clinical auxiliary diagnosis index.
