Expressions of D2-40, CD31 and CD34 in splenic vascular tumors
10.3760/cma.j.issn.1007-8118.2012.02.003
- VernacularTitle:D2-40、CD31、CD34在脾脏脉管瘤中的表达及意义
- Author:
Rongrong ZHANG
;
Jiayi WAN
- Publication Type:Journal Article
- Keywords:
Spleen;
Vascular tumor;
Immunohistochemistry
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(2):88-90
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathologic features,differential diagnoses and pathogenesis of splenic vascular tumors.Methods The records of 7 patients with splenic vascular tumors were reviewed.Immunohistochemical studies were performed by EnVision assay.Results The histopathologic diagnoses were hemangioma (n=2),lymphangioma (n=2) and hemolymplangioma (n=3 ).Positive immunoreactivity of CD31 and CD34 was found in vascular endothelial cells,and D2-40 expression was only identified in lymphatic endothelial cells.Conclusions Immunohistochemical staining of D2-40,CD31,CD34 was very helpful in the diagnosis of splenic vascular tumors.
