The impact of different hepatic vascular occlusion methods on hepatic parenchymal function in partial hepatectomy
10.3760/cma.j.issn.1007 8118.2012.02.005
- VernacularTitle:不同肝脏血流阻断技术对术中吲哚青绿滞留试验的影响
- Author:
Zhaoran SU
;
Weidong JIA
;
Geliang XU
;
Jinliang MA
;
Jiansheng LI
;
Yongsheng GE
;
Jihai YU
- Publication Type:Journal Article
- Keywords:
Hepatocellular carcinoma;
Hepatectomy;
Indocyanine green;
Hepatic inflow occlusion;
Liver function reserve
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(2):96-98
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of different hepatic vascular inflow occlusion methods on hepatic parenchymal function in partial hepatectomy.Methods Between 2009 and 2010,62 hepatocellular carcinoma (HCC) patients underwent partial hepatectomy.In 13 patients,partial hepatectomy was carried out without using any inflow occlusion (group A).In 29 patients intermittent Pringle's maneuver (group B) while in 20 patients selective hepatic inflow occlusion (group C) were used.Intraoperative indocyanine green retention rate at 15 minutes (ICGR15) was measured using pulse spectrophotometry before and during hepatectomy. Results (1) Blood loss in group A was greater than group B and C (P=0.016,P=0.001).(2) There was no significant difference in the preoperative ICGR15 values among group A,B and C.The intraoperative ICGR15 for group B was significantly higher than group A and C (P=0.011,P=0.030).(3) A significant correlation was found between the level of ICGR15 and total inflow clamp time (r =0.484,P =0.001) and blood loss (r=0.349,P=0.005),respectively.(4) Compared with group A and B,postoperative liver function recovered significantly faster in group C.Conclusion Selective hepatic inflow occlusion was useful in controlling blood loss and it was beneficial to the hepatic functional reserve in the liver remnant.
