Experience and procedure of the model of rat heterotopic heart transplantation
10.3760/ema.j.isan.1008-1372.2012.02.011
- VernacularTitle:大鼠异位心脏移植(Ono术式)的流程及经验体会
- Author:
Guohua GAI
;
Zhendong SUN
;
Feng QI
;
Jiaji LEI
;
Liwei DIAO
;
Qinghua ZHANG
;
Naishi WU
- Publication Type:Journal Article
- Keywords:
Heart transplantation/MT;
Transplantation,homologous;
Transplantation,heterotopic
- From:
Journal of Chinese Physician
2012;14(2):182-184
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo summarize the method and experience of the model of rat heterotopic heart transplantation and to improve the rate of success of the experiment.Methods120 heterotopic heart transplantations were performed by Ono's way,including 60 prepared transplantations and 60 formal transplantations.ResultsRate of success of prepared transplantations was 45％,and formal transplantation was 85％.Mean time of formal operation was (74.3±17.1)min,removal time of the donor heart was (7.9±4.2)min,ischemia time was (29.6±10.3) min and the survival time of allograft was (11.1±5.7)days.5 of the recipients had a long-term survival,and the maximum weight was 740 g.ConclusionsGood surgical technique and rigorous perioperative management is very important in setting up the rat model of heterotopic heart transplantation.
