Killing efficacy of chlorine-releasing agents on multidrug-resistant Acinetobacter baumannii
10.3760/cma.j.issn.1674-2397.2012.01.002
- VernacularTitle:含氯消毒剂对多重耐药鲍曼不动杆菌杀灭效果的研究
- Author:
Rujin JIANG
;
Jianming ZHU
;
Kangle WU
- Publication Type:Journal Article
- Keywords:
Acinetobacter baumannii;
Drug resistance,multiple;
Disinfectants
- From:
Chinese Journal of Clinical Infectious Diseases
2012;05(1):5-8
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the killing efficacy of chlorine-releasing agents (CRAs) with different concentrations on multidrug-resistant Acinetobacter baumannii.Methods Totally 30 clinical strains of multidrug-resistant Acinetobacter baumannii were collected from November 2008 to December 2009.Killing efficacy of CRAs on these strains was evaluated by quantitative suspension test.The one-way analysis of variance was performed.Results The log values of killing to 30 strains of multidrug-resistant Acinetobacter baumannii were all ≥5.00,when the bacteria were exposed to available chlorine concentrations 400 mg/L of CRAs for 10 min,600 mg/L for 10 min,800 mg/L for 3 min and 1000 mg/L for 1 min,respectively.And effective rates were all 100％. Furthermore,there were significant differences among different available chlorine concentrations exposed for the same time ( except 10 min) ( F =72.72,64.79 and 32.33,P =0.00),and among different exposure time in the same available chlorine concentration ( except 1000 mg/L) ( F =110.42,20.41 and 3.20,P=0.00,0.00 and 0.03).Conclusion Satisfactory killing efficacy of CRAs to multidrug-resistant Acinetobacter baumannii can be achieved with available chlorine concentration 500 mg/L to 1000 mg/L and exposure time 10 min to 30 min.
