Impact of early lactate clearance rate on damage control surgery in patients with severe trauma
10.3760/cma.j.issn.1673-4904.2012.03.008
- VernacularTitle:严重创伤患者行损伤控制外科对早期乳酸清除率的影响研究
- Author:
Wenxue SONG
;
Jiaxuan WU
;
Yongzhong ZHAO
;
Wanfu LI
;
Shuyong MA
;
Jing XU
;
Yong WANG
- Publication Type:Journal Article
- Keywords:
Wounds and injuries;
Damage control surgery;
Lactate clearance rate
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(3):18-20
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo monitor the early blood lactic acid concentration of patients with severe trauma who have been experienced routine surgery or damage control surgery,and explore the influence of surgical methods for the early lactate clearance rate.MethodsSelected 40 patients with severe trauma,they were divided into two groups with 20 cases each in accordance with the adopted operation mode,reference group by damage control surgery,and control group by routine surgery.Recorded acute physiology and chronic health evaluation Ⅱ (APACHE Ⅱ ) in patients after admission,blood lactic acid concentration at 6 h after admission and admission,calculated the early lactate clearance rate.ResultsIn reference group,blood lactic acid concentration at 6 h after admission was significantly lower than that in control group[ (3.5 ± 1.1 )mmol/L vs.(4.2 ± 1.4) mmol/L,P＜ 0.05 ],early lactate clearance rate was higher than that in control group [ (24.6 ± 6.3 )％ vs.( 11.4 ± 5.3 )％,P＜ 0.05 ].Conclusions Damage control surgery in patients with severe trauma in favour of the early removal of lactic acid,maintaining the homeostasis of the organism,is the key to improve the achievement ratio of treatment with severe trauma.
