Color Doppler ultrasonography in monitoring thrombosis of lower limb deep vein after malignantthoracic tumor surgery
10.3760/cma.j.issn.1671-7368.2012.03.032
- VernacularTitle:超声监测胸外科肿瘤术后低分子肝素预防深静脉血栓效果的观察
- Author:
Na MA
;
Xiujie HAN
;
Huaibin WANG
;
Chuanyu WANG
;
Wenli JIANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Venous thrombosis
- From:
Chinese Journal of General Practitioners
2012;11(3):231-233
- CountryChina
- Language:Chinese
-
Abstract:
Sixty patients underwent surgery for malignant thoracic tumor were evenly randomized into control group (group A) and treatment group (group B).0.3 ml low-molecular-weight heparin was injected per 12 h for 3 d in group B from 24 h after surgery.Bilateral venous sonography of lower extremities were performed before and d1,d3 after operation.Blood coagulation marks PLT,PT,APTT,Fibrinogen (FIB)and D-dimer were determined at the same time.Diagnosis of calf vein thrombosis after surgery was confirmed by color Doppler sonography in 7 patients:1 in group B (3％) and 6 in group A (20％) (P ＜ 0.05 ).Thrombosis at calf intermuscular vein was found in 6 patients and thrombosis at posterior tibial vein in 1 patient.FIB and D-dimer had no significant difference on the dl ( P ＞ 0.05 ) between two groups,but significantly lower on the d3 after surgery in group B than that in group A ( P ＜ 0.05 ).Low-molecularweight heparin reduced blood hypercoagulation state and thrombosis.Color Doppler sonography can be a valuable method for detecting asymptomatic deep vein thrombosis in the early stage after surgery and monitoring the efficacy of thrombosis prevention.
