Incidence of depression and related factors in rheumatoid arthritis

VernacularTitle:类风湿关节炎合并抑郁状态的发生率及相关因素分析
Author: Zhenhua WEN ; Jingyang LI ; Xiaowen LUO ; Ping SHAO
Publication Type:Journal Article
Keywords: Arthritis,rheumatoid; Depressive disorder; Cross-sectional study
From: Chinese Journal of Rheumatology 2012;16(2):120-123
CountryChina
Language:Chinese
Abstract: ObjectiveTo survey the incidence of depression in rheumatoid arthritis (RA) and explore the related factors.MethodsOne hundred and fifty-nine patients with RA were investigated.All of them were assessed by depression scale and Hamilton Depression Rating Scale.A mono-variate and multivariate Logistic regression analysis were carried out to determine the factors that best related to the occurrence of depression in RA.ResultsThe overall incidence rate was 39.6％.The regression analysis showed that factors related to the occurrence of depression in RA were HAQ-DI (OR=3.276,95％CI 1.315-7.814,P=0.003),the number of tender joints (OR=2.252,95％CI 1.117-3.362,P=0.029),low-income families (OR=1.629,95％CI 1.215-2.437,P=0.031 ) and serum CRP level (OR=1.528,95％CI 1.112-2.294,P=0.040).ConclusionDepression is common in patients with RA.Patients who havehigh HAQ-DI,CRP and from low-income families with more tender joints tend to develop depression.