Identification value of contrast-enhanced sonography on peripheral pulmonary cancer
10.3760/cma.j.issn.1004-4477.2012.02.010
- VernacularTitle:超声造影对周围型肺癌的鉴别诊断价值
- Author:
Beilei CHEN
;
Pintong HUANG
;
Feng YE
;
Limin CHEN
;
Peizhen HUANG
;
Jun HE
;
Gang LIU
;
Xiangao JIANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Lung neoplasms;
Diagnosis,differential
- From:
Chinese Journal of Ultrasonography
2012;21(2):124-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of the differential diagnosis of peripheral pulmonary cancer using contrast-enhanced ultrasound (CEUS).MethodsTotally 59 patients selected with peripheral pulmonary lesions(27 primary lung cancer and 32 non-lung cancer cases including 12 pulmonary abscess,19 tuberculosis and 1 hemangioma subjects)were examined by traditional gray-scale sonography and color Doppler flow imaging (CDFI),the lesions shape,borders,echo characteristic and blood flow were recorded first,and then the contrast enhancedsonographicstudies were performed.The process of contrast enhancement and regression was observed and the parameters were quantitative analyzed by acoustic quantification analysis software (ACQ).Finally,surgery or biopsy were conducted.Results CEUS had higher detection rates of blood flow signals than CDFI( P ＜0.001 ).There were significant differences (P ＜ 0.01) between the primary lung cancer group and the non-lung cancer group regarding parameters peak intensity ( PI ) and enhanced intensity ( EI ).By drawing the ROC curve and obtaining the area under the curve:a cut-off value＞15.7 dB of PI in assessing lung cancer had higher sensitivity and specificity (66.7 ％,81.2％).A cut-off value＞ 10.77 dB of EI in assessing lung cancer had higher sensitivity and specificity (81.5％,68.8％).Conclusions CEUS is helpful to identify necrotic tissue in biopsy and improving the biopsy positive rate.The parameters of PI and EI can help to identify the primary lung cancer with the Nonlung cancer.
