A pilot study on Lauren classification of advanced gastric carcinoma using virtual touch tissue quantification
10.3760/cma.j.issn.1004-4477.2012.01.011
- VernacularTitle:声触诊组织量化技术对进展期胃癌Lauren分型的初步研究
- Author:
Ying TANG
;
Pintong HUANG
;
Yi ZHANG
;
Chao ZHANG
;
Yan YANG
;
Zhiqiang ZHENG
;
Zongmin WANG
;
Xueli ZHU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Stomach neoplasms;
Lauren classification;
Virtual touch tissue quantification
- From:
Chinese Journal of Ultrasonography
2012;21(1):31-34
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the value of virtual touch tissue quantification (VTQ) in evaluating Lauren classification of advanced gastric carcinoma.MethodsForty-one patients with gastric cancer proved by endoscopic biopsy performed preoperative VTQ examination,and the findings were compared with postoperative pathologic results via hematoxylin -eosin and Alcian Blue-Periodic Acid Schiff (AB-PAS) staining.ResultsIn 41 patients,26 cases were diagnosed as diffuse type and 15 cases as intestinal type by pathology after operation.The shear wave velocity(SWV) of diffuse type was higher than that of intestinal type [(1.72± 0.83)m/s vs (1.05± 0.66)m/s,t =2.819,P=0.008] measured by virtual touch tissue quantification (VTQ).According to the area under the ROC curve,the cut- off value of SWV in gastric cancer tissues for assessing the diffuse type was 1.045 m/s with a sensitivity of 80.8％ and specificity of 73.3 ％ respectively.ConclusionsVTQ could be considered as a promising method to distinguish the Lauren classification in patients with advanced gastric carcinoma.
