Electrophysiological features of triggering atrial premature contraction in patients with hypertension combined paroxysmal atrial fibrillation
10.3760/cma.j.issn.1008-6315.2012.03.008
- VernacularTitle:原发性高血压伴阵发性心房颤动患者触发性房性期前收缩的电生理研究
- Author:
Zhongliang YANG
;
Nailing WANG
;
Baoling SUN
;
Jian LI
;
Weidong LIU
- Publication Type:Journal Article
- Keywords:
Hypertension;
Paroxysmal atrial fibrillation;
Coupling interval;
Prematurity index
- From:
Clinical Medicine of China
2012;28(3):248-250
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the electrophysiological features of triggering atrial premature contraction(APC) in patients with hypertension combined paroxysmal atrial fibrillation (PAf).Metbods The originating sites and prematurity index (PI) of triggering APC were analyzed in 46 PAf patients with hypertension (hypertension group)and in 35 PAf patients without hypertension( non-hypertension group)from April,2008 to March,2011 in Shanghai Punan Hospital of Pudong New District.Results Triggering APCs in 46 cases with hypertension combined PAf in the hypertension group originated mainly in the left atrium( 81.6% ).The coupling interval (CI)of triggering APC in hypertension group was significantly shorter than that in non-triggering APC ( [ 374.1 ± 31.5 ] ms versus [ 443.6 ± 32.6 ] ms,t =23.361,P < 0.001 ) and that in triggering APC in nonhypertensive group ( [374.1 ±31.5]ms versus [395.7 ±38.2]ms,t =5.549,P <0.001 ).PI in triggering APC was lower than that in non-triggering APC in hypertension group(0.50 +0.05 versus 0.63 ±0.06,t =22.544,P < 0.001 ) and that in triggering APC in non-hypertension group (0.50 + 0.05 versus 0.55 ± 0.08,t =5.849,P < 0.001 ).Conclusion The triggering APC in patients with hypertension combined PAf mainly originates in the left atrium,the PI of triggering APC is significantly lower than that in non-hypertension patients with PAf and PAf occurs more easily in patients with hypertension.Prompt measures should be taken for hypertension patients with lower prematurity index to prevent the occurrence of PAf.