Value of fetal cardiac axis measured in the fetal echocardiography of the second trimester
10.3760/cma.j.issn.1004-4477.2012.01.014
- VernacularTitle:中孕中期胎儿心轴角度的参考值及对心脏畸形诊断的价值
- Author:
Yun ZHANG
;
Yonghao GUI
;
Yingliu YAN
;
Wei ZHAO
;
Xiaowei HUANG
;
Ying YAO
;
Fanbin KONG
;
Yunyun REN
;
Yuqing ZHOU
;
Chen CHU
;
Jizi ZHOU
- Publication Type:Journal Article
- Keywords:
Ultrasonography,prenatal;
Cardiac axis;
Heart defects,congenital
- From:
Chinese Journal of Ultrasonography
2012;21(1):39-41
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the reference ranges for fetal cardiac axis in the mid-second trimester and to evaluate the use of fetal cardiac axis in prenatal diagnosis.Methods 6744 unselected singleton pregnancies were enrolled from September 2008 to October 2010.Routine screening scan of second trimester and fetal echocardiography were performed at 18- 23+6 weeks gestation.Fetal cardiac axis was measured on the four-chamber view of the heart.Results The 6744 fetuses had a mean cardiac axis of (37.03 ± 6.10)°,ranging from 9.80° to 102.41°. Using above or below 95％ range of population (26.63° -49.40°) as a cut-off,there were significant difference of cardiac axis between normal group [(36.96 ± 5.91)°,P ＜0.01] and the group with heart defects [(43.12 ± 15.67)°,P ＜0.01],the group with intrathoricic anomalies or abdominal wall defect [(51.74 ± 15.97)°].ConclusionsThe reference ranges of fetal cardiac axis for local population in mid-second trimester may helpful for detecting congenital defects.Presence of an abnormal cardiac axis in the fetuses is associated with a substantial risk of congenital heart disease and/or other extra cardiac defects.
