Clinical application of real-time shear wave elastography in diagnosis of benign and malignant thyroid solid nodules
10.3760/cma.j.issn.1004-4477.2012.01.018
- VernacularTitle:实时剪切波弹性成像在甲状腺实性结节良恶性鉴别诊断中的临床应用
- Author:
Chao FU
;
Kefei CUI
;
Shicheng QING
;
Ruifang ZHANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Thyroid nodule;
Diagnosis,differential
- From:
Chinese Journal of Ultrasonography
2012;21(1):49-51
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the clinical value of Young's modulus by supersonic shear wave elastography (SWE) in differential diagnosis of thyroid solid nod1ules.MethodsEighty-three patients with 113 solid nodules were examined by SWE.All the nodules were confirmed by pathology.According to Young's modulus,a receiver operating characteristic (ROC) curve was drawn,and it used to identify the value of optimal operating point for differential diagnosis of thyroid nodules.Results ① The mean of Young's modulus of benign nodules was (23.57 ± 9.35)kPa,which was significantly different from the valve of malignant nodules (43.73 ± 19.82) kPa ( t =6.31,P =0.00).(②) It showed that the optimal operating point of ROC curve as 27.49,with high sensitivity(93.2％),specificity(81.2％) and accuracy (85.8％).The area under ROC curve was 0.91.Conclusions SWE is a newly quantitative technique of ultrasonography,which is helpful to identify and distinguish in the differential diagnosis of thyroid nodules.
