Correlation analysis between thyroid nodules and metabolic syndrome and its components
10.3760/cma.j.issn.1000-6699.2012.02.010
- VernacularTitle:甲状腺结节与代谢综合征及其组分的相关性分析
- Author:
Chunyu ZHANG
;
Hongli ZENG
;
Ying LIU
;
Benli. SU
- Publication Type:Journal Article
- Keywords:
Thyroid nodules;
Metabolic syndrome;
Prevalence;
Obesity;
Correlation
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(2):132-135
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the prevalence of thyroid nodules and metabolic syndrome,and to analyze the correlation between thyroid nodules and the components of metabolic syndrome.MethodsThis cross-sectional study included 8 217 people in our hospital health check-up center.Height,body weight,blood pressure,blood glucose,lipid profile,and liver function were measured and ultrasonic scanning of thyroid was performed.Metabolic syndrome was diagnosed according to criteria of CDS/2004.Results ( 1 ) The prevalence of thyroid nodules was 42.1％.The prevalence in women (49.6％) was significantly higher than that in men( 38.4％,P＜0.01.),and it was progressively increased with aging in both sexes.(2) The overall prevalence of metabolic syndrome was 21.7％.The prevalence in men( 28.5％ ) was significantly higher than that in women( 12.8％,P＜0.01 ),and was increased with age until 70 years old.( 3 ) Body mass index,systolic pressure,diastolic pressure,blood glucose,triglyceride in subject with thyroid nodules (TN) were higher than those in subjects without ( non-TN,P＜0.05 ).No difference in the levels of HDL-C was found between cases with TN and non-TN ( P＞0.05 ).(4) Logistic regression analysis revealed that the existence of thyroid nodules was significantly associated with overweight/obesity ( OR =1.263,95 ％ CI 1.134-1.407 ) after adjusting age and sex.Conclusion( 1 ) The prevalences of thyroid nodules and metabolic syndrome are high,and both prevalence increase with advancing age.(2) Obesity or overweight might be a risk factor for the development of thyroid nodules.
