Adult Intracranial Gliofibroma : A Case Report and Review of the Literature.
10.3340/jkns.2016.59.3.302
- Author:
Ho KANG
1
;
Jin Wook KIM
;
Young Bem SE
;
Sung Hye PARK
Author Information
1. Department of Neurosurgery, Seoul National University Hospital, Seoul, Korea. wook616@hanmail.net
- Publication Type:Case Report
- Keywords:
Gliofibroma;
Intracranial tumor
- MeSH:
Adult*;
Central Nervous System Neoplasms;
Classification;
Female;
Humans;
Meningioma;
Middle Aged;
Temporal Lobe;
World Health Organization
- From:Journal of Korean Neurosurgical Society
2016;59(3):302-305
- CountryRepublic of Korea
- Language:English
-
Abstract:
Gliofibroma is an extremely rare biphasic tumor with an astrocytic and benign mesenchymal component, which commonly occurs within the first two decades of life. The exact biological behavior of the tumor is not fully understood. Therefore, it is not listed as a distinct entity in the current World Health Organization classification of central nervous system tumors. Here, we describe a rare case of gliofibroma, which was located on the medial temporal lobe in a 61-year-old woman. Preoperatively, we misdiagnosed it as a meningioma because it was a well-demarcated and well-enhanced extra-axial mass with calcification and bony destruction. On the histopathological and immunohistochemical examination, the tumor consisted of a mixture of glial tissue and mesenchymal tissue and it was finally diagnosed as a gliofibroma. To our knowledge, this case of intracranial gliofibroma is in the oldest patient ever reported.
