The experimental study on application of gastrobiliary duct drainage in primary suture after exploration of common bile duct
10.3760/cma.j.issn.1007-8118.2011.08.019
- VernacularTitle:术中置胃胆管、胆总管一期缝合在胆总管探查术中的应用
- Author:
Qing CHEN
;
Erbin WU
;
Zijian GUO
;
Yong ZHANG
;
Saimin DAI
;
Jiangong GUO
;
Peng ZHOU
;
Junjing ZHOU
- Publication Type:Journal Article
- Keywords:
Gastrobiliary duct drainage;
Primary suture;
Exploration of common bile duct
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(8):652-655
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish an animal model with installation of gastrobiliary duct drainage (GBDD) in the primary suture after exploration of common bile duct, to assess the safety and feasibility of GBDD. Methods Thirty dogs were randomly divided into three groups: control group (n=5), primary suture group (n= 10) and GBDD group (n= 15). Serum TBil levels, bile leakage,and complications were observed and compared. Results No increase in serum TBil level was observed in the control group. However, serum TBil levels were significantly increased in the primary suture group compared to the GBDD group (P<0. 01). GBDD were all successfully withdrawn at mean (7. 0±1.7) days after the operation. No bile leakage was found in the GBDD group, which was significantly different compared to 5/10 bile leakage cases in primary suture group (P<0. 05). There were 3/10 cases of bile peritonitis, infection of incisional wound and splitted in the primary suture group, while there were no such complications in the GBDD group (all P>0.05). Conclusions GBDD is safe and feasible. It can shorten biliary drainage time and prevent occurrence of bile leakage.Therefore, it has unique value in clinical application.