Survivability of hand foot mouth disease virus in tap water

VernacularTitle:手足口病病原在自来水中的存活能力
Author: Wen ZHU ; Lufang JIANG ; Liwen JU ; Qianli WANG ; Haiyan XIONG ; Qingwu JIANG
Publication Type:Journal Article
Keywords: Hand,foot and mouth disease; Enterovirus A,human; Survival rate; Water supply; Disease transmission
From: Chinese Journal of Infectious Diseases 2011;29(8):455-458
CountryChina
Language:Chinese
Abstract: Objective To evaluate the survivability of hand foot mouth disease(HFMD)virus,in tap water for daily use.Methods HFMD viruses were isolated from cases of HFMD in Shanghai and Zhejiang from in 2008.Six isolated strains (five subtype of enterovirus 71 and one coxackie virus)were selected in this study.These viruses were mixed with chloride 1.0 mg/L tap-water and then inoculated into Vero cells.The cytopathic effect (CPE)was checked everyday in order to survey the survivability of each virus strain.The decline of virus survivability was analyzed by scatter diagram.Results These six strains of HMFD virus could survive longer than one month in tap water with initial chloride concentration of 1.0 mg/L and still had celluar infectivity.The survivabilities were varied between viruses isolated from different HFMD cases.Conclusions The survivabilities of enterovirus 71 and coxackie virus stains are quite strong in water.Therefore,the transmission route of water-borne pathogens should be monitored in regions using tap water during HFMD epidemic period.