Ezscan: A new non-invasive technology to evidence cardiac autonomic neuropathy in diabetes

VernacularTitle:Ezscan——一种无创检测糖尿病心血管自主神经并发症的新技术
Author: Xiaolin CAI ; Zhihong YANG ; Zhaoyun ZHANG ; Renming HU
Publication Type:Journal Article
Keywords: Ezscan; Sudomotor function; Diabetes mellitus; Diabetic autonomic neuropathy; Heart rate variability
From: Chinese Journal of Endocrinology and Metabolism 2011;27(8):631-633
CountryChina
Language:Chinese
Abstract: Objective To assess the efficacy of Ezscan in evaluating the risk of cardiac autonomic neuropathy (CAN) in diabetes. Methods This study included 144 patients with diabetes. Their serum lipid profile and HbA1c were determined. The heart rate variability was assessed by Holter, and the cardiac autonomic neuropathy by classic experiments. Meanwhile, Ezscan was carried out. Results There was a positive correlation between low frequency (LF) measurements by Holter and Ezscan score( r=0. 39, P＜0. 01 ), so did LF/HF and Ezscan score( r=0. 28, P＜0. 01 ). Correlations between Ezscan score and other Holter parameters were weaker. There was no correlation between HbA1c and LF measurements. In patients with positive classic experiments, the sensitivity and specificity of Ezscan were 58. 3% and 57.8% respectively. Conclusions Ezscan test is a valuable screening procedure for detecting diabetic complications. It is more facilitative and takes shorter time than does the classical autonomic function assessment.