The clinical efficacy of standardized house dust mite allergen immunotherapy for rhinitis and asthma in children
10.3760/cma.j.issn.1673-4912.2011.04.015
- VernacularTitle:标准化屋尘螨变应原特异性免疫治疗对儿童变应性鼻炎合并哮喘的临床疗效
- Author:
Dongming HUANG
;
Xiaoxiong XIAO
;
Biyun CUI
;
Keming WANG
;
Lan LI
;
Simao FU
- Publication Type:Journal Article
- Keywords:
Specific immunotherapy;
Allergic rhinifis;
Asthma;
Children
- From:
Chinese Pediatric Emergency Medicine
2011;18(4):335-337
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of standardized house dust mite allergen specific immunotherapy (SIT) for rhinitis and asthma in children. Methods Forty-two children with allergic rhinitis and asthma who received a standardized house dust mite allergen SIT in our hospital were enrolled in our study. The result of allergen skin prick test, serum specific IgE levels (sIgE) of house dust mite and dust mite,pulmonary function and symptom scores were analysed before and at one year after treatment in all children. Results Skin indexes of house dust mite and dust mite, symptom score were significantly decreased at one year after treatment,but the levels of house dust mite and dust mite sIgE,lung function test (FVC,FEVt,MEF25-75) showed no significant differences. Conclusion Children with allergic rhinitis and asthma have significant improvements in their skin sensitivity and clinical symptoms by given SIT for one year,but the impact of SIT on airway inflammation needs further observation.
