Strategies to improve the efficacy of liver transplantation for hepatocellular carcinoma
10.3760/cma.j.issn.1673-9752.2011.04.004
- VernacularTitle:提高肝癌肝移植疗效的策略
- Author:
Jian ZHOU
;
Jia FAN
;
Zheng WANG
;
Zhaoyou TANG
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Liver transplantation;
Recurrence;
Metastasis
- From:
Chinese Journal of Digestive Surgery
2011;10(4):253-255
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma(HCC)is a major cause of cancer mortality worldwide,and liver transplantation (LT)has the potential to improve the survival for patients with HCC.However,tumor recurrence after LT remains the main obstacles for long-term survival.Selection of the ideal recipients based on Milan criteria or Shanghai Fudan criteria is a key point to reduce the incidence of recurrence.C,enomics and proteomics combined with tumor specific tumor markers detection are helpful to screen out the recipients.The norms of rumor-free operation should be strictly followed intraoperatively.Preventive chemotherapy and evaluation of immune function should be considered postoperatively to reduce the risks of tumor recurrence and metastasis.
